Possible blood test for Alzheimer’s
Alzheimer’s blood test edges closer
By James GallagherHealth and science reporter, BBC News
29 July 2013 Last updated at 02:02
Researchers believe they are closer to developing a blood test that could diagnose Alzheimer’s.
There is no definitive test for the brain-wasting disease. Doctors rely on cognition tests and brain scans.
A technique published in the journal Genome Biology showed differences in the tiny fragments of genetic material floating in the blood could be used to identify patients.
The test was accurate 93% of the time in trials on 202 people.
One of the main goals of Alzheimer’s research is to find ways of detecting the disease earlier.
It starts years before symptoms appear and it is thought that future treatments will need to be given before large parts of the brain are destroyed. This will require new ways of testing for the condition.
The team at the Saarland University, in Germany, analysed 140 microRNAs (fragments of genetic code) in patients with Alzheimer’s disease and in healthy people.
They found 12 microRNAs in the blood which were present in markedly different levels in people with Alzheimer’s. These became the basis of their test.
Early trials showed it was successful and was “able to distinguish with high diagnostic accuracies between Alzheimer’s disease patients and healthy” people.
However, more research to improve accuracy and to see whether it would work in the clinic is still needed before the test would be considered as a way of diagnosing patients.
Dr Eric Karran, from the charity Alzheimer’s Research UK, said: “This is an interesting approach to studying changes in blood in Alzheimer’s and suggests that microRNAs could be playing a role in the disease.
“The findings highlight the importance of continuing research efforts to understand the contribution of microRNAs to Alzheimer’s, but the translation of this into a blood test for Alzheimer’s in the clinic is still some way off.
“A blood test to help detect Alzheimer’s could be a useful addition to a doctor’s diagnostic armoury, but such a test must be well validated before it’s considered for use. We need to see these findings confirmed in larger samples and more work is needed to improve the test’s ability to distinguish Alzheimer’s from other neurological conditions.”
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- Alzheimer’s Blood Test Edges Closer (feeds.socialpsychology.org)
- Blood Test Over 95% Accurate in Identifying Alzheimer’s Patients (medicaldaily.com)
- Possible blood test for Alzheimer’s disease? (sciencedaily.com)
(some) Comments. I have taken away many on this repost, all comments can be found at the original page
That really sums up what suicide really is to other people and I think it is a true statement.
I am really touched with all the personal stories and also the support, I was expecting a lot of people to really condemn this.
Thanks you for your comment Mary.
Takes alot of courage to share that with everyone…
Thank you for sharing your lessons.
Hi Rishi, thanks for your comments, I really appreciate them.
Thanks to your dad for hearing the bang on the floor because otherwise you wouldn’t be able to share yourself and your story to help others. We are all grateful.
Hi Mary, The good thing that has came out of this is that I tell me family every time I speak to them that I love them, more so my mum and two sisters but I have told my dad on many occasions as well
You are real strong now. Who would point out something like this? Very few people would even think to. It’s easy to look at it from our view as a potent article, but it is completely different to choose to write it and then write it. It makes us stronger just to read it.
One aspect we see is CYT, and CYT would not be here without one individual. We see CYT as a strong presence, and have to remember the strong individual behind it.
I have told folks “Steven Aitchison from Change Your Thoughts said [X] and [Y]” sometimes. I say it in a way that leads folks to assume that I see you as a powerhouse.
Many people have thoughts similar to the ones you had, and some acted as you had, but so few will mention it at a later time.
“the jacket can be altered to fit me and I didn’t have to fit the jacket”
You lose nothing when you mention something important like this, but some of us will see this and then still keep our important things hidden. Maybe it is needed that we get that feeling that we can’t help but point them out.
.-= Armen Shirvanian´s last blog ..Team Up With A Partner To Make Progress =-.
Armen, I can’t begin to tell you how much I have appreciated your support and writing over the last few months. I really appreciate your kind words. You are right in that I am strong, always have been, I just didn’t realise it at times, just like so many others as well.
Dear Steve, you are a delight and I am so glad you are here. Your writing on your blog- and now you- are important to me (way down in Australia) . Thanks heaps for sticking around and for your bravery in posting this!
HI Gareth. I will always regret doing what I did because of the pain it caused to my family so I know where you’re coming from with regards to your friend.
Thanks for commenting Gareth and sharing a part of your own story.
Steven, Thank you for sharing your story. It is truely incredible that you eventually realised what your issues were.
I too, went through something similar. I was not happy with life or the life that I had although I had everything too.
What was getting me down was that I was in a relationship I was not happy in, plus I had found out I was pregnant. I was unhappy because I had no close friends (Due to my relationship) and was increasingly sad. I took pills, but not enough to do me or my baby damage. It was more a cry for help.
After that, I realised I needed to change my life. After my son was born, I ended my relationship with his dad and started going to church. This was exactly what I needed at that time and it has changed me forever. I made the right friends and had a hectic social life which I loved. It also helped me to find me. What I liked and disliked, how I wanted my life to be, not what everyone else wanted my life to be. I had the time to do a lot of soul searching.
Everyone is now amazed at my strength and courage now , but I guess in life, we have to go through these rough times to get the strengh to overcome them.
Thank you again for sharing. I hope it helps many people out there who are going through trials and need a wake-up call. Ending your life is never the best way.